1 Research and instrumental development fro the construction
    of the stimoceiver was supported by the United States Air
    Force, 6571st Aeromedical Research Laboratory F 29600-67-C-
    0058.  Additional support for our research was provided by
    the United States Public Health Service, M-2004, and the 
    Office of Naval Research, 609 (48).

    The circuit for EEG recording is a modified version of the
    unit described by Meehan (1965), and his help in providing
    us with the information and one of his units is gratefully
    acknowledged.  The help of Mr. Per Ha...[unreadable]
    developing telestimulation is also gratefully acknowledged.

During the last few years, methodology has been developed to stimulate
and record the electrical activity of the brain in completely unrestrained
monkeys and chimpanzees (Delgado, 1967; Delgado and Mir, in press).  This
procedure should be of considerable clinical interest because it permits
exploration of the brain for unlimited periods without disturbing their
rest or normal spontaneous activities. [EW: Dr. Delgado, you are all heart!]

This paper reports instrumentation used and clinical application in four
patients with psychomotor epilepsy in whom electrodes had been implanted in
the temporal lobes.  To our knowledge, this is the first use of intercereb-
ral radio stimulation and recording in man.

METHODS
page 185

Implantation of electrodes

Electrodes were constructed and stereotaxically implanted according to 
methods previously described (Mark & Ervin, 1969).  The electrode assemblies
which were connected to a McPherson skull plug, consisted of a plastic 
stylet, 1.2 mm in diameter, with 15 stainless steel ? mm wide contacts at
3 mm intervals, plus one thermistor and three other contacts at the tip.

Using a McPherson Type 2 stereotaxic machine (Mark & Ervin, 1969), electrode
assemblies were implanted ???laterally into the anterior medical amygdala 
of each patient.

Radio Stimulation

This system consists of two instruments:  (1) the RF transmitter that 
measures 30 cm x 25 cm x 15 cm and includes the circuitry for controlling
repetition rate, duration, and amplitude (intensity) of the stimulating
pulse.  The repetition rate may be varied in steps between 10 and ?? Hz
and the duration between 0.1 and 1.5 millisec.  Single pulses may also
be generated.

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