 Neuroscience at The University of BirminghamCNS Trauma
IntroductionHead and spinal cord injury resulting in paralysis is a devastating clinical
problem in the developed world. It strikes our youngest people the hardest
two thirds of all injuries occur in the under 30 age group. Damaged central
nervous system (CNS) nerves cannot regenerate. At present there are no clinical
therapies available to promote reconnection of severed neuronal pathways
and restoration of function. However, it has become clear that CNS nerves
are not innately incapable of regeneration after injury. It is the CNS environment
that limits nerve growth and, given a permissive environment, nerves of
the brain and spinal cord can make good attempts at regrowth. Hence, there
are now extensive programmes of basic and clinical research directed towards
changing the environment of the CNS wound into one which promotes regeneration
and facilitates functional repair.
Groups at the University of Birmingham
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